Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 2/20 | 0.31 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687865 | 0.87 | MEN1 (0.32) | MEN1GAPDHPOLBKMT2ATDP1 | |
| SCHEMBL12687653 | 0.84 | — | — | |
| SCHEMBL8648444 | 0.70 | PBRM1 (0.32) | MEN1GAPDHPOLBKMT2ATDP1 | |
| SCHEMBL8744726 | 0.70 | USP2 (0.36) | MEN1GAPDHPOLBKMT2ATDP1 | |
| SCHEMBL8744701 | 0.70 | VDR (0.32) | MEN1KMT2AKDM4EPBRM1 | |
| SCHEMBL16433665 | 0.70 | ALDH1A1 (0.32) | MEN1GAPDHPOLBKMT2ATDP1 | |
| SCHEMBL12687656 | 0.70 | ACHE (0.35) | ALDH1A1 | |
| SCHEMBL12687654 | 0.67 | BCHE (0.30) | — | |
| SCHEMBL449604 | 0.66 | SMN1; SMN2 (0.42) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL449518 | 0.66 | SMN1; SMN2 (0.42) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |