Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 9/20 | 0.66 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.66 |
| ▸ | ITGAL | P20701 | 9/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 3/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744772 | 1.00 | ITGB2 (0.66) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL9595504 | 0.87 | MAPT (0.71) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL8744700 | 0.87 | MAPT (0.71) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL3728145 | 0.87 | ALOX15 (0.70) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL13278205 | 0.87 | ALOX15 (0.70) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL29987387 | 0.87 | ALOX15 (0.70) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL11591677 | 0.85 | ECE1 (0.71) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL28046779 | 0.85 | ECE1 (0.71) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL11863617 | 0.84 | ITGB2 (0.67) | ITGB2ICAM1ITGALPOLBMEN1 | |
| SCHEMBL11873118 | 0.84 | ITGB2 (0.63) | ITGB2ICAM1ITGALPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |