Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841689 | 0.78 | TDP1 (0.70) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL66892 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL990038 | 0.78 | TDP1 (0.70) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL23319717 | 0.76 | TDP1 (0.94) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL28043814 | 0.76 | TDP1 (0.94) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL28043559 | 0.76 | TDP1 (0.94) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL7407338 | 0.76 | TDP1 (0.94) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL11372580 | 0.76 | TDP1 (0.67) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL22710108 | 0.76 | TDP1 (0.67) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL15212378 | 0.76 | TDP1 (0.94) | TDP1ALDH1A1TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628026-B1 | CYANO-OXIME ETHERS, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE | BASF AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| CN-1081676-A | The indoles and the indazole derivatives that are used for the treatment and the prevention of cerebral disorders, their preparation and application | SANKYO CO (JP) | 1994-02-09 | — | — | CN | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |