Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875318 | 0.94 | KMT2A (0.46) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL874410 | 0.94 | HTT (0.54) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL878191 | 0.94 | ALDH1A1 (0.49) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL875418 | 0.92 | KMT2A (0.45) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL875017 | 0.92 | HTT (0.47) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL877579 | 0.92 | KMT2A (0.50) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL874677 | 0.90 | PRMT1 (0.45) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL875118 | 0.90 | TSHR (0.52) | KMT2AKDM4EMEN1MMP2 | |
| SCHEMBL874387 | 0.89 | KMT2A (0.48) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL874194 | 0.88 | ALOX15 (0.48) | KMT2AKDM4EALDH1A1MEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619185-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038942-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |