Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744885 | 0.87 | ALDH1A1 (0.44) | AKR1C1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL8744879 | 0.76 | ALDH1A1 (0.41) | AKR1C1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL11211096 | 0.72 | RAB9A (0.39) | AKR1C1UNGLMNAMAPTKMT2A | |
| SCHEMBL8744893 | 0.69 | ALDH1A1 (0.34) | ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL2747632 | 0.69 | ESR1 (0.63) | AKR1C1PRMT1ATMTDP1L3MBTL1 | |
| SCHEMBL2747630 | 0.69 | ESR1 (0.63) | AKR1C1PRMT1ATMTDP1L3MBTL1 | |
| SCHEMBL15969887 | 0.68 | AKR1C3 (0.48) | AKR1C1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL15052966 | 0.68 | AKR1C3 (0.48) | AKR1C1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL14130850 | 0.68 | AKR1C3 (0.48) | AKR1C1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL15969889 | 0.68 | TDP1 (0.43) | MAPTKMT2AALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |