Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864697 | 0.86 | SIGMAR1 (0.76) | KDM4EALDH1A1TDP1KDM4CPOLB | |
| SCHEMBL6862996 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1TDP1KDM4CNPSR1 | |
| SCHEMBL18998084 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1TDP1KDM4CNPSR1 | |
| SCHEMBL8691440 | 0.82 | DRD4 (0.70) | ALDH1A1ITGB3ITGA2BHTR7MAPT | |
| SCHEMBL11898006 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1TDP1KDM4CNPSR1 | |
| Hydrochloric Acid SCHEMBL8690310 | 0.81 | DRD4 (0.68) | ITGB3ITGA2BHTR7 | |
| SCHEMBL2111769 | 0.80 | SIGMAR1 (0.67) | KDM4EALDH1A1TDP1CYP1A2CYP3A4 | |
| SCHEMBL8744966 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1MEN1KMT2AITGB3 | |
| SCHEMBL18998037 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1TDP1KDM4CNPSR1 | |
| SCHEMBL7043039 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1TDP1KDM4CNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |