Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 6/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421666 | 0.86 | AKR1B1 (0.50) | IAPPSLC22A12BACE1SLC2A9AKR1B1 | |
| SCHEMBL17595074 | 0.86 | AKR1B1 (0.50) | IAPPSLC22A12BACE1SLC2A9AKR1B1 | |
| SCHEMBL4638602 | 0.84 | IAPP (0.57) | IAPPBACE1 | |
| SCHEMBL10907538 | 0.80 | IAPP (0.50) | IAPPGABRA1GABRB2HTT | |
| SCHEMBL29755788 | 0.80 | IAPP (0.50) | IAPPGABRA1GABRB2HTT | |
| Acetic Acid SCHEMBL16679832 | 0.78 | GABRA1 (0.58) | IAPPAKR1B1GABRA1GABRB2HTT | |
| SCHEMBL11399077 | 0.77 | SLC22A12 (0.44) | SLC22A12BACE1SLC2A9AKR1C3 | |
| SCHEMBL11399081 | 0.77 | SLC22A12 (0.44) | SLC22A12BACE1SLC2A9AKR1C3 | |
| SCHEMBL5489366 | 0.76 | CTBP2 (0.47) | SLC22A12BACE1SLC2A9AKR1C3HTT | |
| SCHEMBL11395760 | 0.76 | CTBP2 (0.47) | SLC22A12BACE1SLC2A9AKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649063-B1 | Matted radiation-sensitive recording material | AGFA GEVAERT AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0649063-A1 | Matted radiation-sensitive recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-19 | — | — | EP | disclosed |