SCHEMBL8745129

SCHEMBL8745129

[CH2]CCC(=O)OCc1cc[c]cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
MAPK1 P28482 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KMT2A Q03164 4/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19095329 0.82 ALDH1A1 (0.42) ALDH1A1MAPK1L3MBTL1KMT2AMAPT
SCHEMBL6050075 0.81 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1KMT2AMAPT
SCHEMBL8894766 0.79 ALDH1A1 (0.54) ALDH1A1KMT2AMAPTMEN1POLB
SCHEMBL11286167 0.78 TDP1 (0.64) ALDH1A1MAPK1L3MBTL1KMT2AMAPT
SCHEMBL9672601 0.78 ALDH1A1 (0.44) ALDH1A1MAPK1L3MBTL1KMT2AMEN1
SCHEMBL8745093 0.77 CYP2C19 (0.37) ALDH1A1MAPK1KMT2AMEN1POLB
SCHEMBL11279085 0.74 ALDH1A1 (0.79) ALDH1A1MAPK1L3MBTL1KMT2ALMNA
SCHEMBL11043580 0.73 RAB9A (0.59) ALDH1A1MAPK1L3MBTL1KMT2AMAPT
SCHEMBL11276134 0.73 FFAR1 (0.54) ALDH1A1MAPK1L3MBTL1KMT2AMAPT
SCHEMBL3878195 0.73 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP claimed
US-5210289-A Homo or coploymers for medical diagnosis EASTMAN KODAK COMPANY (US) 1993-05-11 US claimed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US claimed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP claimed
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP disclosed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP disclosed
EP-0468585-B1 Biologically active reagent, analytical element and methods for use of the reagent JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-08 EP disclosed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP disclosed
US-5330891-A Method for detection of a nucleic acid using particulate reagent having polyoxyalkylene side chains EASTMAN KODAK COMPANY (US) 1994-07-19 US disclosed
US-5278267-A Water insoluble vinyl aromatic polymer EASTMAN KODAK COMPANY (US) 1994-01-11 US disclosed
US-5262297-A Medical diagnosis with active materials bound to polymers EASTMAN KODAK COMPANY (US) 1993-11-16 US disclosed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US disclosed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US disclosed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US disclosed
EP-0468585-A2 Biologically active reagent, analytical element and methods for use of the reagent Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 EP disclosed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP disclosed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed