SCHEMBL8745199

SCHEMBL8745199

CCC1CCC(C2CCC(CC=O)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1710143 0.93 ALDH1A1 (0.40) ALDH1A1MAPK1TDP1
SCHEMBL1509950 0.83 TLR4 (0.38) ALDH1A1
SCHEMBL9625923 0.83 TLR4 (0.38) ALDH1A1
SCHEMBL9625925 0.83 TLR4 (0.38) ALDH1A1
SCHEMBL10486367 0.80 KDM4E (0.33) ALDH1A1
SCHEMBL10485941 0.80 KDM4E (0.33) ALDH1A1
SCHEMBL10703702 0.80 KDM4E (0.33) ALDH1A1
SCHEMBL76463 0.80
SCHEMBL1249367 0.79 CYP1A2 (0.47) ALDH1A1MAPK1
SCHEMBL24017656 0.79 ALDH1A1 (0.36) ALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7226644-B2 Chroman derivative and liquid-crystal composition containing the compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-05 US disclosed
US-7226644-B2 Chroman derivative and liquid-crystal composition containing the compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-05 US disclosed
EP-0563981-B1 Cis-1,4-substituted 2-butene derivative CHISSO CORP (JP) 1997-01-22 EP disclosed
US-5401434-A Cis-1,4-substituted 2-butene derivative CHISSO CORPORATION (JP) 1995-03-28 US disclosed
EP-0563981-A2 Cis-1,4-substituted 2-butene derivative Chisso Corporation (JP) 1993-10-06 EP disclosed