Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27962418 | 0.86 | KCNH2 (0.43) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL4533966 | 0.86 | EPHX2 (0.46) | EPHX2PDE2AHCRTR1HCRTR2P2RX7 | |
| SCHEMBL13557302 | 0.83 | PDE2A (0.44) | EPHX2PDE2AHCRTR1HCRTR2KCNH2 | |
| SCHEMBL8745263 | 0.83 | EPHX2 (0.47) | EPHX2PDE2AHCRTR1HCRTR2KCNH2 | |
| SCHEMBL1569028 | 0.80 | EPHX2 (0.45) | EPHX2PDE2AHCRTR1HCRTR2KCNH2 | |
| SCHEMBL1568961 | 0.79 | EPHX2 (0.44) | EPHX2PDE2AHCRTR1HCRTR2P2RX7 | |
| SCHEMBL25182236 | 0.79 | EPHX2 (0.50) | EPHX2PDE2AHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2441170 | 0.79 | PDE2A (0.46) | EPHX2PDE2AHCRTR1HCRTR2P2RX7 | |
| SCHEMBL6468220 | 0.79 | PDE2A (0.46) | EPHX2PDE2AHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2447332 | 0.79 | EPHX2 (0.50) | EPHX2PDE2AHCRTR1HCRTR2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |