Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393296 | 0.81 | ALDH1A1 (0.41) | CYP2C19POLBALDH1A1 | |
| SCHEMBL8752789 | 0.77 | CHRNB2 (0.36) | ALDH1A1 | |
| SCHEMBL8745127 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8752786 | 0.76 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL17861693 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL8745180 | 0.75 | POLB (0.33) | CYP2C19POLBALDH1A1HPGDLMNA | |
| SCHEMBL8745145 | 0.75 | CYP2C19 (0.40) | PPARACYP2C19ALDH1A1HPGDMEN1 | |
| SCHEMBL8433054 | 0.75 | CYP2C19 (0.35) | CYP2C19POLBALDH1A1HPGDLMNA | |
| SCHEMBL8417981 | 0.74 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL8745131 | 0.73 | FOLH1 (0.34) | CYP2C19POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0462670-B1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0462644-B1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-10-18 | — | — | EP | claimed |