Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745225 | 0.96 | LSS (0.37) | LSSMAOBKCNH2DRD2HTR2A | |
| SCHEMBL8745212 | 0.90 | MAOB (0.41) | MAOBKCNH2DRD2HTR2AHTR2C | |
| SCHEMBL8745216 | 0.87 | MAOB (0.41) | MAOBKCNH2DRD2HTR2AHTR2C | |
| SCHEMBL9135731 | 0.86 | MAOB (0.39) | MAOBKCNH2DRD2HTR2AHTR2C | |
| SCHEMBL8745156 | 0.86 | TNNC1 (0.38) | MAOBDRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8745332 | 0.84 | MAOB (0.39) | MAOBKCNH2DRD2HTR2AHTR2C | |
| SCHEMBL8745311 | 0.83 | TNNC1 (0.43) | KCNH2TNNC1 | |
| SCHEMBL8745269 | 0.83 | GRIK1 (0.37) | TNNC1 | |
| SCHEMBL8745261 | 0.83 | TNNC1 (0.36) | MAOBDRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8745162 | 0.82 | TNNC1 (0.48) | HTR2AHTR2CTNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |