Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745156 | 0.96 | TNNC1 (0.38) | TNNC1TRPA1SLC6A4SLC6A3GRM2 | |
| SCHEMBL8745626 | 0.91 | TRPA1 (0.35) | TRPA1SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL8745245 | 0.88 | SLC6A4 (0.35) | TRPA1SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL8745225 | 0.87 | LSS (0.37) | TNNC1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8745282 | 0.87 | TNNC1 (0.41) | TNNC1MAPTLMNA | |
| SCHEMBL8745176 | 0.86 | NFE2L2 (0.36) | TNNC1TRPA1MAPTNFE2L2 | |
| SCHEMBL8745161 | 0.86 | NFE2L2 (0.38) | TRPA1SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL8745150 | 0.86 | TNNC1 (0.45) | TNNC1SLC6A4SLC6A3TP53HTR2A | |
| SCHEMBL8745203 | 0.86 | TNNC1 (0.45) | TNNC1MAOBMAOA | |
| SCHEMBL8745248 | 0.84 | GRIK1 (0.35) | TNNC1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |