Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745354 | 0.91 | NPC1 (0.47) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8745349 | 0.88 | NPC1 (0.47) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL9492756 | 0.83 | NPC1 (0.49) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8745371 | 0.77 | NPC1 (0.42) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8745444 | 0.75 | NPC1 (0.46) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8745391 | 0.75 | NPC1 (0.46) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8745393 | 0.75 | NPC1 (0.46) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8894780 | 0.72 | ALDH1A1 (0.52) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL8894790 | 0.72 | ALDH1A1 (0.52) | NPC1POLBALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL5743648 | 0.71 | ALDH1A1 (0.49) | NPC1POLBALDH1A1CHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276143-A | Dideoxyfructonucleosides and deoxyfructonucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |