Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745349 | 0.88 | NPC1 (0.47) | NPC1POLBKMT2AMEN1CYP1A2 | |
| SCHEMBL8745381 | 0.78 | NPC1 (0.40) | NPC1POLBKMT2AMEN1CYP1A2 | |
| SCHEMBL8745345 | 0.77 | NPC1 (0.47) | NPC1POLBKMT2AMEN1CYP1A2 | |
| SCHEMBL8447329 | 0.76 | CHRNB2 (0.41) | NPC1POLBALDH1A1GAALMNA | |
| SCHEMBL8745354 | 0.75 | NPC1 (0.47) | NPC1POLBKMT2AMEN1CYP1A2 | |
| SCHEMBL23797087 | 0.70 | ALDH1A1 (0.48) | NPC1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL20729515 | 0.70 | ALDH1A1 (0.48) | NPC1POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9492756 | 0.70 | NPC1 (0.49) | NPC1POLBKMT2AMEN1CYP1A2 | |
| SCHEMBL8745366 | 0.69 | MAPT (0.50) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28498515 | 0.69 | MAPK1 (0.50) | NPC1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276143-A | Dideoxyfructonucleosides and deoxyfructonucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |