Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | EPOR | P19235 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874041 | 0.78 | MAPK1 (0.39) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16344478 | 0.77 | MEN1 (0.45) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL2325119 | 0.76 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL2332173 | 0.76 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL910747 | 0.76 | KCNH2 (0.58) | ITGB3ITGA2BFFAR1S1PR1S1PR3 | |
| SCHEMBL17919109 | 0.76 | KMT2A (0.46) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16383768 | 0.76 | ALDH1A1 (0.46) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16383914 | 0.76 | KMT2A (0.46) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11932186 | 0.74 | KCNH2 (0.46) | ITGB3ITGA2BFFAR1 | |
| SCHEMBL16853286 | 0.74 | LTA4H (0.56) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | The Regents of the University of Michigan (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040527-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | WO | disclosed |