Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691489 | 1.00 | HPGD (0.55) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL29564585 | 0.85 | HPGD (0.53) | HPGDALOX15MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL29564409 | 0.84 | HPGD (0.51) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL4448945 | 0.83 | HPGD (0.54) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL4448947 | 0.83 | HPGD (0.54) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL23771133 | 0.82 | ALDH1A1 (0.50) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL9468478 | 0.82 | HSD17B10 (0.50) | ALOX15MEN1KMT2AMAPTLMNA | |
| SCHEMBL23771092 | 0.82 | ALDH1A1 (0.50) | HPGDALOX15MEN1KMT2AMAPT | |
| Methane SCHEMBL8701106 | 0.82 | HPGD (0.53) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL17263871 | 0.81 | ALDH1A1 (0.53) | HPGDMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755404-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-01-29 | — | — | EP | disclosed |