Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPRA | P18433 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632109 | 1.00 | SLC6A2 (0.52) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| SCHEMBL5180745 | 1.00 | SLC6A2 (0.52) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| Hydrochloric Acid SCHEMBL2210722 | 0.98 | SMN1; SMN2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| Hydrochloric Acid SCHEMBL1311456 | 0.98 | SMN1; SMN2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| Hydrochloric Acid SCHEMBL2210717 | 0.98 | SMN1; SMN2 (0.50) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| Methyl Alcohol SCHEMBL11329639 | 0.97 | SMN1; SMN2 (0.49) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| SCHEMBL1811750 | 0.91 | FDPS (0.46) | SLC6A2TAAR1SMN1; SMN2HIF1ABLM | |
| SCHEMBL540243 | 0.84 | BLM (0.67) | BLMPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL503525 | 0.84 | BLM (0.67) | BLMPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL503526 | 0.84 | BLM (0.67) | BLMPTPN2PTPN1PTPRAPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030469-A1 | THERAPEUTIC MITOCHONDRIAL PEPTIDES | COHBAR, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021030749-A1 | THERAPEUTIC PEPTIDES | COHBAR, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| EP-3668886-A2 | TAU AGGREGATION PEPTIDE INHIBITORS | Adrx, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036725-A2 | TAU AGGREGATION PEPTIDE INHIBITORS | ADRX, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2018156892-A1 | PEPTIDE INHIBITORS OF TRANSCRIPTION FACTOR AGGREGATION | ADRX, INC. (US) | 2018-08-30 | — | — | WO | disclosed |
| EP-3303367-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | New York University (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016201007-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY (US) | 2016-12-15 | — | — | WO | disclosed |
| CN-1211232-A | Benzamidine derivatives substituted with amino acid and hydroxy acid derivatives and their use as anticoagulants | BERLEX LAB (US) | 1999-03-17 | — | — | CN | disclosed |
| US-5610145-A | CARBAMATE STEREOISOMERS | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0755404-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028418-A2 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-10-26 | — | — | WO | disclosed |