Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 3/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.51 |
| ▸ | CHRNG | P07510 | 3/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.51 |
| ▸ | CHRND | Q07001 | 3/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | CTSC | P53634 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747743 | 0.84 | MME (0.44) | CTSCCTSL | |
| SCHEMBL18689376 | 0.81 | CTSL (0.57) | GRIA1CTSLCTSS | |
| SCHEMBL2184414 | 0.81 | NAALAD2 (0.48) | — | |
| SCHEMBL8412847 | 0.81 | CTSL (0.51) | KMT2ACTSLCTSBCTSSMEN1 | |
| SCHEMBL27718746 | 0.81 | GRIA1 (0.45) | CHRNDCTSCGRIA1CTSL | |
| SCHEMBL2183861 | 0.81 | MME (0.41) | CTSC | |
| SCHEMBL27899225 | 0.81 | CTSC (0.56) | CHRNDCTSC | |
| SCHEMBL9143188 | 0.81 | CTSC (0.67) | CTSC | |
| SCHEMBL10724398 | 0.81 | CTSL (0.56) | ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL8893265 | 0.81 | CTSC (0.67) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755404-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-01-29 | — | — | EP | claimed |
| WO-1995028418-A2 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-10-26 | — | — | WO | disclosed |