Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689376 | 0.94 | CTSL (0.57) | CTSLCTRB1PTPN1CA2CTSS | |
| SCHEMBL40779 | 0.91 | CTRB1 (0.58) | CTSLNPC1RAB9ACTRB1PTPN1 | |
| SCHEMBL40780 | 0.91 | CTRB1 (0.58) | CTSLNPC1RAB9ACTRB1PTPN1 | |
| SCHEMBL8745478 | 0.81 | PSMB8 (0.51) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL28473692 | 0.80 | CTSL (0.64) | CTSLPTPN1CTSSCTSKCTSB | |
| SCHEMBL9143188 | 0.79 | CTSC (0.67) | CTSK | |
| SCHEMBL7288504 | 0.79 | CTSL (0.56) | CTSLCTRB1CTSSCTSKCTSB | |
| SCHEMBL8893265 | 0.79 | CTSC (0.67) | CTSK | |
| SCHEMBL10724398 | 0.79 | CTSL (0.56) | CTSLCTRB1CTSSCTSKCTSB | |
| SCHEMBL5996736 | 0.79 | CTSC (0.67) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986136-A | Photolabeling reagent | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-11-16 | — | — | US | claimed |
| US-5986136-A | Photolabeling reagent | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-11-16 | — | — | US | disclosed |