Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142649 | 0.83 | KDM4E (0.45) | — | |
| SCHEMBL30281019 | 0.83 | KDM4E (0.45) | — | |
| SCHEMBL17555901 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL17583342 | 0.79 | KDM4E (0.57) | — | |
| SCHEMBL30622679 | 0.79 | KDM4E (0.57) | — | |
| SCHEMBL17555848 | 0.79 | HRH4 (0.53) | HRH3 | |
| SCHEMBL8415184 | 0.79 | EPHX2 (0.59) | HTR2CHRH3EPHX2PLD1 | |
| SCHEMBL17583291 | 0.77 | SCN10A (0.40) | HRH3 | |
| Hydrochloric Acid SCHEMBL8705460 | 0.77 | EPHX2 (0.58) | HTR2CEPHX2PLD1 | |
| SCHEMBL13116668 | 0.76 | HTR2C (0.56) | HTR2CEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389368-B1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1997-01-29 | — | — | EP | disclosed |