Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689496 | 0.82 | MAPT (0.46) | MAPTALDH1A1MAPK1POLBTDP1 | |
| SCHEMBL11010761 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1MAPK1GPR174POLB | |
| SCHEMBL11011738 | 0.79 | POLB (0.60) | MAPTALDH1A1MAPK1GPR174POLB | |
| SCHEMBL11008789 | 0.76 | MAPT (0.45) | MAPTALDH1A1MAPK1GPR174POLB | |
| SCHEMBL9437320 | 0.73 | GRM5 (0.41) | MAPTALDH1A1MAPK1GPR174POLB | |
| SCHEMBL10969474 | 0.70 | KMT2A (0.55) | MAPTALDH1A1GPR174RAB9AGAA | |
| SCHEMBL10964799 | 0.70 | MAPT (0.55) | MAPTALDH1A1MAPK1GPR174POLB | |
| SCHEMBL2982554 | 0.70 | MAPT (0.43) | MAPTALDH1A1MAPK1POLBTDP1 | |
| SCHEMBL16284339 | 0.69 | MAPT (0.54) | MAPTALDH1A1MAPK1GAALMNA | |
| SCHEMBL9437322 | 0.69 | GRM5 (0.41) | MAPTALDH1A1MAPK1GPR174POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389368-B1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1997-01-29 | — | — | EP | disclosed |
| EP-0389369-B1 | New 3-oxo-steroids with an amino substituted chain in position 17 a procedure for their production and intermediates of this procedure, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1994-11-09 | — | — | EP | disclosed |
| EP-0389370-B1 | 19-Nor 3-keto steroids with an amine substituted 17-chain, method for their production and intermediates thereof. Their use as medicines and pharmaceutical composition containing them | ROUSSEL UCLAF (FR) | 1994-04-27 | — | — | EP | disclosed |
| US-5302719-A | Antiinflammatory and antioxidant | ROUSSEL UCLAF (FR) | 1994-04-12 | — | — | US | disclosed |
| US-5202316-A | Antiinflammatory agent | ROUSSEL UCLAF (FR) | 1993-04-13 | — | — | US | disclosed |
| US-5081113-A | Antioxidants, Antiinflammatory Agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| EP-0389369-A1 | New 3-oxo-steroids with an amino substituted chain in position 17 a procedure for their production and intermediates of this procedure, their use as medicines and pharmaceutical preparations containing them | ROUSSEL-UCLAF (FR) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389370-A1 | 19-Nor 3-keto steroids with an amine substituted 17-chain, method for their production and intermediates thereof. Their use as medicines and pharmaceutical composition containing them | ROUSSEL-UCLAF (FR) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389368-A1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1990-09-26 | — | — | EP | disclosed |