SCHEMBL8745609

SCHEMBL8745609

CCCC([NH])Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.48
NPSR1 Q6W5P4 5/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 5/20 0.44
HTT P42858 3/20 0.44
UBE2N P61088 2/20 0.44
GLA P06280 1/20 0.44
MITF O75030 1/20 0.44
RAB9A P51151 3/20 0.40
RAD52 P43351 2/20 0.40
STAT3 P40763 1/20 0.40
RCE1 Q9Y256 1/20 0.40
APAF1 O14727 1/20 0.40
HSP90AA1 P07900 1/20 0.40
NOD2 Q9HC29 1/20 0.40
NPC1 O15118 2/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536663 0.84 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11741919 0.84 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10883621 0.84 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9322305 0.81 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12646310 0.80 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7107870 0.79 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5489761 0.79 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7227225 0.79 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8083828 0.79 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9770169 0.78 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459458-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-02-12 EP disclosed
EP-0331096-B1 Silver halide photographic light-sensitive material capable of obtaining high contrast images KONISHIROKU PHOTO IND (JP) 1995-10-04 EP disclosed
US-5268261-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-07 US disclosed
US-4988603-A RAPID DEVELOPMENT OF SILVER HALIDE PHOTOGRAPHIC MATERIAL; PHOTOSENSITIVITY; HIGH DOT QUALITY KONICA CORPORATION (JP) 1991-01-29 US disclosed
US-4977063-A Silver halide photographic light-sensitive material capable of obtaining high contrast images KONICA CORPORATION (JP) 1990-12-11 US disclosed
EP-0331096-A2 Silver halide photographic light-sensitive material capable of obtaining high contrast images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0324391-A2 Method for the formation of high-contrast images KONICA CORPORATION (JP) 1989-07-19 EP disclosed