SCHEMBL8745864

SCHEMBL8745864

CC1(C)CC([N])CC(C)(CN)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11575222 0.78 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL19217559 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL18473954 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL13334597 0.76 ESR1 (0.35) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL8739143 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL15383 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL8739288 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL21147091 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL20604028 0.76 ALDH1A1 (0.33) ALDH1A1CYP3A4MEN1KMT2A
SCHEMBL24030719 0.74 FUCA1 (0.34) ALDH1A1CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757980-A1 Process for the preparation of 3-aminomethyl-3,5,5-trimethyl cyclohexylamine BASF AKTIENGESELLSCHAFT (DE) 1997-02-12 EP disclosed