Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19217559 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL21147091 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL20604028 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL18473954 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL15383 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL8739143 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7183446 | 0.98 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9228552 | 0.98 | MEN1 (0.35) | ALDH1A1CYP3A4MEN1KMT2A | |
| Ethylenediamine SCHEMBL10381584 | 0.96 | ALDH1A1 (0.32) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7189601 | 0.94 | ALDH1A1 (0.31) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2115026-B1 | AMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-8193257-B2 | Amine-initiated polyols and rigid polyurethane foam made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-8193257-B2 | Amine-initiated polyols and rigid polyurethane foam made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-20120129964-A1 | Amine-initiated polyols and rigid polyurethane foam made therefrom | MORLEY TIMOTHY A (CH) | 2012-05-24 | — | — | US | disclosed |
| US-20100036010-A1 | Amine-initiated polyols and rigid polyurethane foam made therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-11 | — | — | US | disclosed |
| US-20100036010-A1 | Amine-initiated polyols and rigid polyurethane foam made therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036010-A1 | Amine-initiated polyols and rigid polyurethane foam made therefrom | PKM, PUF60, PNMT | ALDH1A1 3866/4885CYP3A4 4222/4885MEN1 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.