Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400128 | 0.87 | HDAC1 (0.50) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL23662783 | 0.81 | IAPP (0.53) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL27860624 | 0.79 | EPHX2 (0.51) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL1953231 | 0.78 | EPHX2 (0.59) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL29733422 | 0.78 | EPHX2 (0.59) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL6286074 | 0.78 | MAOB (0.46) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL30257708 | 0.77 | ALDH1A1 (0.50) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL266248 | 0.77 | ALDH1A1 (0.50) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL3233422 | 0.77 | MAOB (0.50) | HDAC1HDAC8CNR1POLBGAA | |
| SCHEMBL5873518 | 0.77 | CNR1 (0.49) | HDAC1HDAC8CNR1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |