Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 12/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745931 | 0.85 | CYP24A1 (0.45) | CYP24A1CYP26A1CYP3A4MEN1KMT2A | |
| SCHEMBL8745925 | 0.80 | MAPT (0.44) | CYP26A1CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL11092000 | 0.74 | CYP3A4 (0.49) | CYP26A1CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL3170149 | 0.74 | CYP17A1 (0.50) | CYP24A1CYP26A1CYP3A4MEN1KMT2A | |
| SCHEMBL8745961 | 0.72 | IDO1 (0.45) | CYP24A1CYP26A1CYP3A4MEN1KMT2A | |
| SCHEMBL8745923 | 0.70 | ACP3 (0.37) | CYP3A4KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9028689 | 0.69 | SCN9A (0.37) | — | |
| SCHEMBL11090079 | 0.68 | CYP24A1 (0.51) | CYP24A1CYP26A1CYP3A4MEN1KMT2A | |
| SCHEMBL25436361 | 0.68 | KDM4E (0.41) | CYP3A4KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8745971 | 0.67 | HDAC4 (0.33) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |