Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 2/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745923 | 0.80 | ACP3 (0.37) | HDAC4CNR2ACP3HSD11B1HTT | |
| SCHEMBL8745940 | 0.76 | CYP3A4 (0.35) | HDAC4CNR2ACP3CTSA | |
| SCHEMBL9028689 | 0.76 | SCN9A (0.37) | CNR2 | |
| SCHEMBL8745941 | 0.74 | ACP3 (0.37) | HDAC4CNR2ACP3HSD11B1SLC6A3 | |
| SCHEMBL8745947 | 0.74 | RIPK1 (0.36) | CTSASMN1; SMN2 | |
| SCHEMBL8745928 | 0.73 | CYP3A4 (0.36) | CNR2 | |
| SCHEMBL8745925 | 0.68 | MAPT (0.44) | ACP3 | |
| SCHEMBL25436361 | 0.68 | KDM4E (0.41) | CNR2ACP3HSD11B1SMN1; SMN2 | |
| SCHEMBL8745938 | 0.67 | CYP24A1 (0.46) | SLC6A3 | |
| SCHEMBL20306574 | 0.63 | LMNA (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |