Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745940 | 0.83 | CYP3A4 (0.35) | ACP3CNR2CYP3A4HSD17B10KDM4E | |
| SCHEMBL8745947 | 0.82 | RIPK1 (0.36) | CYP3A4HSD17B10KDM4ETSHRTDP1 | |
| SCHEMBL8745954 | 0.81 | KDM4E (0.39) | ACP3CNR2CYP3A4HSD17B10KDM4E | |
| SCHEMBL8745928 | 0.81 | CYP3A4 (0.36) | CNR2CYP3A4HSD17B10KDM4ETSHR | |
| SCHEMBL8745971 | 0.80 | HDAC4 (0.33) | ACP3CNR2HTTSMN1; SMN2HSD11B1 | |
| SCHEMBL9028689 | 0.79 | SCN9A (0.37) | CNR2 | |
| SCHEMBL8745925 | 0.73 | MAPT (0.44) | ACP3CYP3A4TDP1CYP2C19CYP2D6 | |
| SCHEMBL8745914 | 0.72 | ACP3 (0.43) | ACP3CNR2CYP3A4HSD17B10TDP1 | |
| SCHEMBL25436361 | 0.70 | KDM4E (0.41) | ACP3CNR2CYP3A4KDM4ETSHR | |
| SCHEMBL8745938 | 0.70 | CYP24A1 (0.46) | CYP3A4TDP1CYP2C19ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |