Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745951 | 0.77 | TSHR (0.41) | HSD11B1MC4RNPFFR1NPFFR2ACP3 | |
| SCHEMBL8753200 | 0.76 | CBLB (0.43) | HSD11B1MC4RACP3OPRM1OPRD1 | |
| SCHEMBL9776265 | 0.73 | ACP3 (0.50) | MC4RNPFFR1NPFFR2ACP3OPRM1 | |
| SCHEMBL30903830 | 0.73 | ACP3 (0.50) | MC4RNPFFR1NPFFR2ACP3OPRM1 | |
| SCHEMBL8745905 | 0.68 | RBP4 (0.40) | HSD11B1MC4RACP3OPRM1OPRD1 | |
| SCHEMBL3289370 | 0.67 | ACP3 (0.57) | ACP3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL30986703 | 0.67 | ACP3 (0.57) | ACP3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3294921 | 0.67 | ACP3 (0.57) | ACP3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13168657 | 0.66 | ACP3 (0.47) | HSD11B1MC4RACP3OPRM1OPRD1 | |
| SCHEMBL29907993 | 0.66 | ACP3 (0.47) | HSD11B1MC4RACP3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |