Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745905 | 0.78 | RBP4 (0.40) | HSD11B1ACP3MC4RALDH1A1LMNA | |
| SCHEMBL8745970 | 0.77 | HSD11B1 (0.41) | HSD11B1ACP3MC4ROPRM1OPRD1 | |
| SCHEMBL9776265 | 0.72 | ACP3 (0.50) | GAAACP3MC4RALDH1A1LMNA | |
| SCHEMBL30903830 | 0.72 | ACP3 (0.50) | GAAACP3MC4RALDH1A1LMNA | |
| SCHEMBL24176794 | 0.70 | CYP1A2 (0.39) | SMN1; SMN2ACP3ALDH1A1LMNACNR2 | |
| SCHEMBL3289370 | 0.69 | ACP3 (0.57) | SMN1; SMN2ACP3CNR2OPRM1OPRD1 | |
| SCHEMBL3294921 | 0.69 | ACP3 (0.57) | SMN1; SMN2ACP3CNR2OPRM1OPRD1 | |
| SCHEMBL30986703 | 0.69 | ACP3 (0.57) | SMN1; SMN2ACP3CNR2OPRM1OPRD1 | |
| SCHEMBL24176795 | 0.68 | TRPC5 (0.39) | ACP3ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL13114035 | 0.67 | LMNA (0.39) | TSHRSMN1; SMN2GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |