Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745916 | 0.80 | GAA (0.59) | HPGDHSD17B10KDM4ECYP19A1IDO1 | |
| SCHEMBL11685401 | 0.80 | GAA (0.41) | HPGDHSD17B10KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8745920 | 0.76 | PIEZO1 (0.38) | KCNA5CYP3A4GAAPRKDCKCNH2 | |
| SCHEMBL8753255 | 0.75 | SMN1; SMN2 (0.58) | HPGDKCNA5KDM4EGAASMN1; SMN2 | |
| SCHEMBL8745958 | 0.75 | GAA (0.42) | HPGDHSD17B10MCL1KCNA5KDM4E | |
| SCHEMBL11632311 | 0.75 | GAA (0.66) | HPGDHSD17B10KCNA5CYP19A1GAA | |
| SCHEMBL28994021 | 0.74 | KDM4C (0.42) | HPGDHSD17B10CYP2C19KDM4EKDM4C | |
| SCHEMBL29976363 | 0.73 | ADRB2 (0.48) | CYP2C19KDM4EIDO1TDO2CYP3A4 | |
| SCHEMBL230382 | 0.73 | ADRB2 (0.48) | CYP2C19KDM4EIDO1TDO2CYP3A4 | |
| SCHEMBL4705342 | 0.72 | HPGD (0.41) | HPGDHSD17B10KCNA5CYP2C19KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |