Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 3/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307648 | 0.85 | LMNA (0.44) | LMNAGAACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL2307646 | 0.85 | LMNA (0.44) | LMNAGAACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL402156 | 0.84 | MEN1 (0.44) | LMNAGAACYP11B1CYP11B2POLQ | |
| SCHEMBL402157 | 0.84 | MEN1 (0.44) | LMNAGAACYP11B1CYP11B2POLQ | |
| SCHEMBL9874152 | 0.83 | LMNA (0.43) | LMNAGAACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL9874146 | 0.83 | LMNA (0.43) | LMNAGAACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL9166573 | 0.78 | LMNA (0.43) | LMNAGAACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL28634751 | 0.72 | LMNA (0.64) | LMNAGAASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL20547611 | 0.71 | CYP11B1 (0.49) | GAACYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL1950901 | 0.71 | CTNNB1 (0.57) | LMNAGAACTNNB1WNT3AF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |