Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874146 | 1.00 | LMNA (0.43) | LMNAGAACYP11B1CYP11B2CTNNB1 | |
| SCHEMBL8745973 | 0.83 | LMNA (0.41) | LMNAGAACYP11B1CYP11B2CTNNB1 | |
| SCHEMBL9166573 | 0.80 | LMNA (0.43) | LMNAGAACYP11B1CYP11B2CTNNB1 | |
| SCHEMBL402156 | 0.79 | MEN1 (0.44) | LMNAGAACYP11B1CYP11B2POLQ | |
| SCHEMBL402157 | 0.79 | MEN1 (0.44) | LMNAGAACYP11B1CYP11B2POLQ | |
| SCHEMBL2307648 | 0.78 | LMNA (0.44) | LMNAGAACYP11B1CYP11B2CTNNB1 | |
| SCHEMBL2307646 | 0.78 | LMNA (0.44) | LMNAGAACYP11B1CYP11B2CTNNB1 | |
| SCHEMBL28634751 | 0.74 | LMNA (0.64) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL9874158 | 0.74 | CYP11B1 (0.54) | CYP11B1CYP11B2 | |
| SCHEMBL13729327 | 0.73 | CES2 (0.53) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5022915-A | Substituted 2,4-diarylpyrimidines and their use as herbicides | ICI AMERICAS INC. (US) | 1991-06-11 | — | — | US | disclosed |