SCHEMBL8745976

SCHEMBL8745976

CCc1cc(Sc2cc(CC)c(O)cc2CC)c(CC)cc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.42
ALOX12 P18054 2/20 0.42
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
MAPT P10636 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPK1 P28482 3/20 0.40
POLB P06746 2/20 0.40
THRB P10828 2/20 0.40
HKDC1 Q2TB90 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MCL1 Q07820 2/20 0.40
HTT P42858 2/20 0.40
APEX1 P27695 1/20 0.40
RECQL P46063 1/20 0.40
CACNA1B Q00975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11672184 0.86 ESR1 (0.41) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL891144 0.83 ALOX15 (0.50) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL30067469 0.83 ALOX15 (0.50) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL1760478 0.83 ALOX15 (0.54) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL2484931 0.79 ALOX15 (0.61) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL29517048 0.79 ALOX15 (0.61) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL14303453 0.78 MAPK1 (0.42) ALOX15ESR1ESR2MAPTMEN1
SCHEMBL6040093 0.78 ALOX15 (0.56) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL9318708 0.78 ALOX15 (0.56) ALOX15ALOX12ESR1ESR2MAPT
SCHEMBL7529793 0.77 ALOX15 (0.35) ALOX15ALOX12ESR1ESR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US claimed
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-0366461-B1 Optical recording medium JUJO PAPER CO LTD (JP) 1997-02-19 EP disclosed
EP-0325231-B1 Heat-sensitive recording material JUJO PAPER CO LTD (JP) 1994-06-22 EP disclosed
US-5281570-A Heat sensitive sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-01-25 US disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed
EP-0307836-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO PAPER CO., LTD. (JP) 1993-04-28 EP disclosed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
US-5075146-A Containing heat sensitive color developable layer on infrared absorbent substrates JUJO PAPER CO., LTD. (JP) 1991-12-24 US disclosed
EP-0154336-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1988-10-26 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
US-4628336-A POLYPHENYL ESTERS; SOIL RESISTANCE; IMAGE STABILITY JUJO PAPER CO., LTD. (JP) 1986-12-09 US disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed
US-4590499-A MONOBENZYL CALCIUM PHTHALATE OR ZINC P-NITROBENZOATE AS STABILIZER IN THE CHROMOGEN LAYER; OIL REPELLENTS JUJO PAPER CO., LTD. (JP) 1986-05-20 US disclosed
US-4573062-A HYDROXYBENZ/YLOXYBENZOIC ACID COLOR DEVELOPER AND LEUCO DYE JUJO PAPER CO., LTD. (JP) 1986-02-25 US disclosed
EP-0171810-A2 Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-02-19 EP disclosed
EP-0168819-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-01-22 EP disclosed
EP-0154336-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-09-11 EP disclosed
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US disclosed