Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 11/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL923473 | 0.85 | SMN1; SMN2 (0.49) | RAPGEF3RAPGEF4MAPTMEN1KMT2A | |
| SCHEMBL924786 | 0.83 | MAPT (0.60) | MAPTMEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL922482 | 0.82 | MAPT (0.64) | RAPGEF3RAPGEF4MAPTMEN1KMT2A | |
| SCHEMBL9877010 | 0.76 | RAPGEF3 (0.66) | RAPGEF3RAPGEF4MAPTNPSR1 | |
| SCHEMBL923266 | 0.72 | MAPT (0.69) | RAPGEF3RAPGEF4MAPTMEN1KMT2A | |
| SCHEMBL20523678 | 0.70 | RAPGEF3 (1.00) | RAPGEF3RAPGEF4MAPTNPSR1 | |
| SCHEMBL11545594 | 0.69 | GAA (0.45) | RAPGEF3RAPGEF4MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL24707370 | 0.69 | DYRK1A (0.55) | — | |
| SCHEMBL24130109 | 0.69 | MEN1 (0.58) | MAPTMEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL5538125 | 0.69 | RAPGEF4 (0.41) | RAPGEF3RAPGEF4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | claimed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | claimed |
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5215924-A | Water immiscibility; ionophore; pH indicator which undergoes color change; sensitizer/stabilizer | BOEHRINGER MANNHEIM GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |