Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746014 | 0.76 | ESR1 (0.55) | ESR1THRATHRBPLA2G4BMAPT | |
| SCHEMBL31734218 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL30517741 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL29794119 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL50769 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL2304857 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL18012379 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL1123538 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL8581954 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA | |
| SCHEMBL29361974 | 0.75 | NPC1 (0.72) | THRATHRBL3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5215924-A | Water immiscibility; ionophore; pH indicator which undergoes color change; sensitizer/stabilizer | BOEHRINGER MANNHEIM GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |