Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817211 | 0.82 | ESR1 (0.56) | ESR1PLA2G4BTHRATHRBMAPT | |
| SCHEMBL8745995 | 0.76 | ESR1 (0.50) | ESR1PLA2G4BTHRATHRBCYP19A1 | |
| SCHEMBL8358189 | 0.74 | ESR1 (0.44) | ESR1PLA2G4BTHRATHRBCYP19A1 | |
| SCHEMBL17817065 | 0.74 | ESR1 (0.50) | ESR1PLA2G4BTHRATHRBMAPT | |
| SCHEMBL590156 | 0.73 | GPR35 (0.59) | MAPTGPR35 | |
| SCHEMBL9322138 | 0.73 | THRA (0.54) | ESR1PLA2G4BTHRATHRBCYP19A1 | |
| SCHEMBL11511728 | 0.72 | ALDH1A1 (0.46) | ESR1PLA2G4BTHRATHRBCYP19A1 | |
| SCHEMBL9699807 | 0.72 | ESR1 (0.48) | ESR1PLA2G4BTHRATHRBMAPT | |
| SCHEMBL6933094 | 0.71 | ESR1 (0.52) | ESR1PLA2G4BTHRATHRBCYP19A1 | |
| SCHEMBL2249192 | 0.71 | ESR1 (0.52) | ESR1PLA2G4BTHRATHRBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0461392-B1 | Test carrier for the determination of ions | BOEHRINGER MANNHEIM GMBH (DE) | 1996-01-10 | — | — | EP | disclosed |
| US-5302346-A | Test carrier for the determination of ions | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| US-5215924-A | Water immiscibility; ionophore; pH indicator which undergoes color change; sensitizer/stabilizer | BOEHRINGER MANNHEIM GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5211914-A | TEST CARRIER FOR THE DETERMINATION OF IONS | BOEHRINGER MANNHEIM GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
| EP-0461392-A2 | Test carrier for the determination of ions | Roche Diagnostics GmbH (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |