Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574609 | 0.88 | GPR35 (0.46) | ESR1GPR35ALDH1A1MAPTTDP1 | |
| SCHEMBL28161418 | 0.82 | ESR1 (0.49) | ESR1GPR35MAPTPLA2G4B | |
| SCHEMBL3184320 | 0.82 | ESR1 (0.49) | ESR1GPR35MAPTPLA2G4B | |
| SCHEMBL28842377 | 0.81 | ESR1 (0.39) | ESR1ALDH1A1MAPTALOX5TDP1 | |
| SCHEMBL5590592 | 0.81 | ALOX5 (0.50) | ESR1GPR35ALDH1A1MAPTALOX5 | |
| SCHEMBL5586564 | 0.81 | ALOX5 (0.50) | ESR1GPR35ALDH1A1MAPTALOX5 | |
| SCHEMBL5586828 | 0.81 | ALOX5 (0.50) | ESR1GPR35ALDH1A1MAPTALOX5 | |
| SCHEMBL5590106 | 0.81 | ALOX5 (0.50) | ESR1GPR35ALDH1A1MAPTALOX5 | |
| SCHEMBL5590328 | 0.81 | ALOX5 (0.50) | ESR1GPR35ALDH1A1MAPTALOX5 | |
| SCHEMBL28424080 | 0.80 | GPR35 (0.44) | GPR35ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0461392-B1 | Test carrier for the determination of ions | BOEHRINGER MANNHEIM GMBH (DE) | 1996-01-10 | — | — | EP | disclosed |
| US-5302346-A | Test carrier for the determination of ions | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| US-5215924-A | Water immiscibility; ionophore; pH indicator which undergoes color change; sensitizer/stabilizer | BOEHRINGER MANNHEIM GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5211914-A | TEST CARRIER FOR THE DETERMINATION OF IONS | BOEHRINGER MANNHEIM GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
| EP-0461392-A2 | Test carrier for the determination of ions | Roche Diagnostics GmbH (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |