Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6947333 | 0.98 | SIGMAR1 (0.44) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL11444001 | 0.92 | SIGMAR1 (0.44) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL8746092 | 0.88 | CSNK1E (0.47) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL28523845 | 0.84 | CSNK1E (0.57) | TP53CSNK1E | |
| SCHEMBL1975377 | 0.82 | TRPA1 (0.50) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL2243355 | 0.82 | TRPA1 (0.50) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL7252952 | 0.81 | EPHX1 (0.55) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL19056797 | 0.81 | SIGMAR1 (0.44) | SIGMAR1TP53 | |
| SCHEMBL6682088 | 0.80 | TDP1 (0.46) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL9456004 | 0.80 | TDP1 (0.46) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117702142-A | C (C) 4 Process for preparing substituted pyridine derivatives | 五邑大学 | 2024-03-15 | — | — | CN | disclosed |
| EP-0758320-A1 | TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS | Allelix Biopharmaceuticals Inc. (CA) | 1997-02-19 | — | — | EP | disclosed |
| US-5504101-A | TRYPTAMINE ANALOGS | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1996-04-02 | — | — | US | disclosed |
| WO-1995030655-A1 | TRYPTAMINE DERIVATIVES AS 5-HT-1D RECEPTOR LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-11-16 | — | — | WO | disclosed |