Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598686 | 0.90 | LMNA (0.66) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL5598683 | 0.90 | LMNA (0.66) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL5379059 | 0.82 | PTPN1 (0.73) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL71401 | 0.82 | PTPN1 (0.73) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL71402 | 0.82 | PTPN1 (0.73) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL2627847 | 0.82 | PTPN1 (0.73) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL31301140 | 0.82 | PTPN1 (0.73) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL23866732 | 0.81 | GSK3B (0.66) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL1614490 | 0.81 | LMNA (0.64) | LMNAMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL11332365 | 0.81 | CA12 (0.68) | LMNAMAPTNPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758350-A1 | PHOTODEGRADABLE POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030701-A1 | PHOTODEGRADABLE POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |
| US-5144003-A | Curable copolymers containing 1,5-bis(4-carboxycyclohexyl)-3-pentanol monomer; castings and moldings | EASTMAN KODAK COMPANY (US) | 1992-09-01 | — | — | US | disclosed |