Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.60 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
| ▸ | IAPP | P10997 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643935 | 0.91 | CYP4A11 (0.66) | CYP4A11CYP4F2LOXL2F2RL1MAPT | |
| SCHEMBL8801049 | 0.85 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2F2RL1MAPT | |
| SCHEMBL10629587 | 0.84 | CYP4A11 (0.58) | CYP4A11CYP4F2LOXL2F2RL1IAPP | |
| SCHEMBL70185 | 0.83 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2MAPTMEN1 | |
| SCHEMBL1629577 | 0.82 | CYP4A11 (0.64) | CYP4A11CYP4F2LOXL2MAPTMEN1 | |
| SCHEMBL2499088 | 0.82 | CYP4A11 (0.64) | CYP4A11CYP4F2LOXL2MAPTHPGD | |
| SCHEMBL661620 | 0.82 | CYP4A11 (0.64) | CYP4A11CYP4F2LOXL2MAPTHPGD | |
| SCHEMBL5648022 | 0.82 | LOXL2 (0.59) | CYP4A11CYP4F2LOXL2MAPTMEN1 | |
| SCHEMBL1807631 | 0.82 | CYP4A11 (0.68) | CYP4A11CYP4F2LOXL2MAPTMEN1 | |
| SCHEMBL13267781 | 0.81 | IAPP (0.61) | CYP4A11CYP4F2F2RL1IAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758350-A1 | PHOTODEGRADABLE POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030701-A1 | PHOTODEGRADABLE POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |
| US-4467112-A | REACTING P-FORMYLBENZOIC ACID OR ESTER WITH KETONE, HYDROGENATION AND REDUCTION OF INTERMEDIATES | KAWASAKI KASEI CHEMICALS LTD. (JP) | 1984-08-21 | — | — | US | disclosed |