SCHEMBL8746233

SCHEMBL8746233

CCN(CC)c1ccc(C(c2ccc(Cl)cc2)(c2ccc(Cl)cc2)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.53
ALDH1A1 P00352 2/20 0.47
PSMD14 O00487 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
GFER P55789 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CNR1 P21554 8/20 0.46
MAPT P10636 1/20 0.44
ALDH3A1 P30838 1/20 0.44
ALDH1A3 P47895 1/20 0.44
DHFR P00374 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13211689 0.89 ALDH1A1 (0.56) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL2881066 0.87 CNR2 (0.63) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL13211710 0.83 ALDH1A1 (0.50) CNR2ALDH1A1PSMD14CYP3A4TSHR
Trimethylammonium SCHEMBL6555079 0.83 CNR2 (0.59) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL6344469 0.83 CNR2 (0.59) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL3490254 0.82 CNR2 (0.53) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL3490247 0.82 CNR2 (0.53) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL12342194 0.82 CNR2 (0.53) CNR2ALDH1A1PSMD14CYP3A4TSHR
Methane SCHEMBL10535102 0.81 CNR2 (0.58) CNR2ALDH1A1PSMD14CYP3A4TSHR
SCHEMBL6278267 0.79 ALDH1A1 (0.54) CNR2ALDH1A1PSMD14CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0491315-B1 Inverse multiactive electrophotographic element EASTMAN KODAK CO (US) 1997-02-26 EP claimed
US-5213927-A Multilayer; electroconductive, charge transport and charge generating layer EASTMAN KODAK COMPANY (US) 1993-05-25 US claimed
EP-0491315-A1 Inverse multiactive electrophotographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-06-24 EP claimed
US-5213927-A Multilayer; electroconductive, charge transport and charge generating layer EASTMAN KODAK COMPANY (US) 1993-05-25 US disclosed
US-4468444-A Pyrylium-sensitized leuco base photoconductive compositions and elements containing naphthalene bis-dicarboximide compounds EASTMAN KODAK COMPANY (US) 1984-08-28 US disclosed