Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 12/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.66 |
| ▸ | PHLPP1 | O60346 | 3/20 | 0.66 |
| ▸ | ILK | Q13418 | 3/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950713 | 0.86 | AKT1 (0.52) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL5771546 | 0.85 | AKT1 (0.70) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL14580950 | 0.85 | AKT1 (0.70) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL18212526 | 0.85 | AKT1 (0.70) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL5771699 | 0.84 | AKT1 (0.69) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL23191967 | 0.82 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL15042781 | 0.82 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL6027769 | 0.82 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL5773613 | 0.82 | AKT1 (0.73) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL8747826 | 0.82 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550337-B1 | Tissue protective tocopherol analogs | MERRELL PHARMA INC (US) | 1997-02-12 | — | — | EP | disclosed |