⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioglycolic Acid SCHEMBL3079958 | 0.92 | — | — | |
| Thioglycolic Acid SCHEMBL9449577 | 0.92 | — | — | |
| Thioglycolic Acid SCHEMBL21017 | 0.91 | — | — | |
| Thioglycolic Acid SCHEMBL134322 | 0.91 | LMNA (0.46) | — | |
| Thioglycolic Acid SCHEMBL23045255 | 0.88 | — | — | |
| Thioglycolic Acid SCHEMBL18783207 | 0.88 | — | — | |
| Thioglycolic Acid SCHEMBL16795985 | 0.88 | FFAR3 (0.53) | — | |
| Thioglycolic Acid SCHEMBL4595079 | 0.88 | FFAR3 (0.53) | — | |
| Thioglycolic Acid SCHEMBL10607018 | 0.88 | — | — | |
| Thioglycolic Acid SCHEMBL11854674 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971327-B | There is the anti-inflammatory compound of multiple tyrosine-kinase enzyme inhibition activity and the pharmaceutical compositions containing these compounds | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-04-20 | — | — | CN | disclosed |
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
| EP-2619185-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| CN-102971327-A | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases, and pharmaceutical composition containing same | KOREA INST SCI & TECH | 2013-03-13 | — | — | CN | disclosed |
| WO-2012038942-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |
| US-5171860-A | Diamino isothiazole-1-oxides and 1,1 dioxides as gastric secretion inhibitors | MERCK & CO., INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-4772433-A | Vitamin D analogues | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0078704-B1 | INTERMEDIATES IN THE SYNTHESIS OF VITAMIN D DERIVATIVES | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1987-04-29 | — | — | EP | disclosed |
| EP-0067436-B1 | DIAMINO ISOTHIAZOLE -1-OXIDES AND -1,1-DIOXIDES AS GASTRIC SECRETION INHIBITORS | MERCK & CO. INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| US-4470981-A | STEROIDS, LOWERING SERUM CHOLESTEROL | HESSE ROBERT H | 1984-09-11 | — | — | US | disclosed |
| EP-0078704-A1 | Intermediates in the synthesis of vitamin D derivatives | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1983-05-11 | — | — | EP | disclosed |
| EP-0067436-A2 | Diamino isothiazole -1-oxides and -1,1-dioxides as gastric secretion inhibitors | MERCK & CO. INC. (US) | 1982-12-22 | — | — | EP | disclosed |
| US-3976769-A | INSECTICIDE | AIRWICK INDUSTRIES, INC. (US) | 1976-08-24 | — | — | US | disclosed |