Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292999 | 0.98 | ELANE (0.44) | ELANEDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL7303909 | 0.96 | ELANE (0.43) | ELANEDPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL7313936 | 0.92 | ELANE (0.41) | ELANE | |
| SCHEMBL6559665 | 0.80 | PSENEN (0.43) | ELANEDPP4DPP8DPP9 | |
| SCHEMBL24850751 | 0.78 | ADAM17 (0.36) | ELANEDPP4DPP8DPP9 | |
| SCHEMBL6558465 | 0.77 | PSENEN (0.41) | ELANE | |
| SCHEMBL6560709 | 0.77 | PSENEN (0.41) | ELANE | |
| SCHEMBL24909282 | 0.77 | ADAM17 (0.36) | ELANEDPP4DPP8DPP9 | |
| SCHEMBL7300414 | 0.76 | ELANE (0.33) | ELANEDPP4DPP8DPP9 | |
| SCHEMBL10448837 | 0.75 | ELANE (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630382-B1 | LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1997-02-26 | — | — | EP | disclosed |