Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560709 | 1.00 | PSENEN (0.41) | PSENENCASP1CTSDELANEMEN1 | |
| SCHEMBL6559665 | 0.97 | PSENEN (0.43) | PSENENCASP1CTSDELANEMEN1 | |
| SCHEMBL6558448 | 0.86 | PSENEN (0.39) | PSENENCASP1CTSDELANE | |
| SCHEMBL6559645 | 0.84 | ALDH1A1 (0.40) | PSENENCTSD | |
| SCHEMBL6558875 | 0.83 | CASP1 (0.42) | PSENENCASP1CTSD | |
| SCHEMBL6558747 | 0.82 | BACE1 (0.42) | PSENENCASP1CTSD | |
| SCHEMBL6558450 | 0.80 | MAGI3 (0.37) | PSENENCASP1CTSD | |
| SCHEMBL6558839 | 0.80 | PSENEN (0.36) | PSENENCASP1CTSDELANE | |
| SCHEMBL6558811 | 0.79 | FURIN (0.46) | — | |
| SCHEMBL20067565 | 0.79 | DPP4 (0.36) | CASP1ELANEMEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |