Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.37 |
| ▸ | CCR7 | P32248 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825251 | 1.00 | CXCR2 (0.37) | CXCR2CCR7TAAR1MPOSLC6A4 | |
| SCHEMBL8746397 | 1.00 | CXCR2 (0.37) | CXCR2CCR7TAAR1MPOSLC6A4 | |
| SCHEMBL9148237 | 1.00 | CXCR2 (0.37) | CXCR2CCR7TAAR1MPOSLC6A4 | |
| SCHEMBL4637623 | 0.98 | CXCR2 (0.38) | CXCR2CCR7TAAR1MPOSLC6A4 | |
| SCHEMBL4610914 | 0.92 | CA2 (0.41) | CXCR2CCR7TAAR1MPOSLC6A4 | |
| SCHEMBL15022605 | 0.84 | TAAR1 (0.54) | TAAR1MPOSLC6A4CA2BCHE | |
| SCHEMBL2339012 | 0.84 | TAAR1 (0.41) | CXCR2CCR7TAAR1MPORIPK1 | |
| SCHEMBL29471378 | 0.84 | TAAR1 (0.41) | CXCR2CCR7TAAR1MPORIPK1 | |
| SCHEMBL1007490 | 0.83 | PTGS2 (0.36) | CXCR2CCR7TAAR1RIPK1BCHE | |
| SCHEMBL2956567 | 0.82 | TAAR1 (0.56) | TAAR1MPOSLC6A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683623-A | FERROELECTRIC LIQUID CRYSTALS CELLS AND DEVICES FOR ELECTROOPTICAL APPARATUS | CENTRAL RESEARCH LABORATORIES LIMITED (GB) | 1997-11-04 | — | — | US | disclosed |
| EP-0662114-B1 | DIOXANE DERIVATIVES | CENTRAL RESEARCH LAB LTD (GB) | 1997-02-19 | — | — | EP | disclosed |
| EP-0662114-A1 | DIOXANE DERIVATIVES. | CENTRAL RESEARCH LAB LTD (GB) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994006885-A1 | DIOXANE DERIVATIVES | CENTRAL RESEARCH LABORATORIES LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |