SCHEMBL8746459

SCHEMBL8746459

CCCCCCCCCOc1cccc(F)c1F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.50
PTPN1 P18031 1/20 0.48
MCHR1 Q99705 2/20 0.48
MEN1 O00255 2/20 0.47
CYP3A4 P08684 2/20 0.47
KMT2A Q03164 2/20 0.47
NR1I2 O75469 1/20 0.47
LMNA P02545 1/20 0.47
CHRM2 P08172 1/20 0.47
ADRA2A P08913 1/20 0.47
MAPT P10636 1/20 0.47
OPRK1 P41145 1/20 0.47
HTR2B P41595 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
GRM2 Q14416 2/20 0.46
FAAH O00519 6/20 0.46
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4826935 1.00 L3MBTL1 (0.54) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL8234319 1.00 L3MBTL1 (0.54) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL8746453 1.00 L3MBTL1 (0.54) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL7781687 1.00 L3MBTL1 (0.54) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL2511831 1.00 L3MBTL1 (0.54) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL8753757 0.98 L3MBTL1 (0.56) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL30625031 0.98 L3MBTL1 (0.56) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL6000380 0.93 L3MBTL1 (0.51) L3MBTL1TDP1PTPN1MCHR1MEN1
SCHEMBL427889 0.93 L3MBTL1 (0.53) L3MBTL1TDP1MCHR1GRM2FAAH
SCHEMBL8216509 0.87 L3MBTL1 (0.50) L3MBTL1TDP1MCHR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5683623-A FERROELECTRIC LIQUID CRYSTALS CELLS AND DEVICES FOR ELECTROOPTICAL APPARATUS CENTRAL RESEARCH LABORATORIES LIMITED (GB) 1997-11-04 US disclosed
EP-0662114-B1 DIOXANE DERIVATIVES CENTRAL RESEARCH LAB LTD (GB) 1997-02-19 EP disclosed
EP-0662114-A1 DIOXANE DERIVATIVES. CENTRAL RESEARCH LAB LTD (GB) 1995-07-12 EP disclosed
WO-1994006885-A1 DIOXANE DERIVATIVES CENTRAL RESEARCH LABORATORIES LIMITED (GB) 1994-03-31 WO disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0517498-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed