Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8753757 | 0.94 | L3MBTL1 (0.56) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL30625031 | 0.94 | L3MBTL1 (0.56) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL2511831 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL8234319 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL8746453 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL7781687 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL8746459 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL4826935 | 0.93 | L3MBTL1 (0.54) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL8216509 | 0.90 | L3MBTL1 (0.50) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL6000380 | 0.90 | L3MBTL1 (0.51) | L3MBTL1CYP1A2CYP2C19CYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102603496-A | Method for synthesizing 1-butoxy-2,3-difluorobenzene | PANJIN XINGFU CHEMICAL CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-114231293-B | Negative dielectric liquid crystal composition and application thereof | 重庆汉朗精工科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110799627-B | 2, 3-dihydrobenzothiophene derivatives | 默克专利股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| US-11174432-B2 | 2,3-dihydrobenzothiophene derivatives | MERCK PATENT GMBH (DE) | 2021-11-16 | — | — | US | disclosed |
| EP-3645662-B1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-03-24 | — | — | EP | disclosed |
| EP-3645662-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-20200123444-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-04-23 | — | — | US | disclosed |
| CN-110799627-A | 2, 3-dihydrobenzothiophene derivatives | 默克专利股份有限公司 | 2020-02-14 | — | — | CN | disclosed |
| WO-2019002196-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |
| CN-105218328-A | A kind of dielectric negative liquid crystal compound and preparation method thereof and application | JIANGSU HECHENG ADVANCED MATERIALS CO LTD | 2016-01-06 | — | — | CN | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
| EP-1835009-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY UTILIZING THE SAME | Dainippon Ink and Chemicals, Incorporated (JP) | 2007-09-19 | — | — | EP | disclosed |
| US-7255900-B2 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-08-14 | — | — | US | disclosed |
| CN-101003468-A | Method for preparing difluoro alkyl ether benzene | KANGPENG CHEMICAL CO LTD SHANG (CN) | 2007-07-25 | — | — | CN | disclosed |
| US-20050258399-A1 | Fluorinated heterocycles and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123444-A1 | 2,3-DIHYDROBENZOTHIOPHENE DERIVATIVES | DDT, MAGT1, MBTD1 | L3MBTL1 1374/4885CYP1A2 943/4885CYP2C19 2484/4885 |
| US-11174432-B2 | 2,3-dihydrobenzothiophene derivatives | DDT, MAGT1, MBTD1 | L3MBTL1 1374/4885CYP1A2 943/4885CYP2C19 2484/4885 |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | HEXD, CFD, EDF1 | L3MBTL1 4349/4885CYP1A2 343/4885CYP2C19 811/4885 |
| US-20050258399-A1 | Fluorinated heterocycles and their use in liquid-crystal mixtures | CHRM1, AFF1, H1-0 | L3MBTL1 510/4885CYP1A2 328/4885CYP2C19 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.